Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT07569588

Improving Patient Assessment After Acute Kidney Injury (AKI)

Sponsor: University of Nottingham

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to improve patient care after acute kidney injury (AKI). It has three related parts. The main questions it aims to answer are: 1. Is creatinine or cystatin a more reliable assessment of kidney function after AKI? 2. What are the experiences of patients after AKI? 3. What interventions should be recommended to improve assessment and support of patients after AKI? Participants will be asked to do one or more of: * blood tests to measure kidney function in different ways * have measurement of their body composition * complete questionnaires about their symptoms * have an interview with a researcher about their experiences * discussion to develop an action plan based on findings

Key Details

Gender

All

Age Range

18 Years - 85 Years

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2026-02-16

Completion Date

2029-10

Last Updated

2026-05-06

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Iohexol renal clearance measurement

Gold standard measurement of glomerular filtration rate.

DIAGNOSTIC_TEST

Cystatin C

Estimated GFR using serum cystatin C

DIAGNOSTIC_TEST

Creatinine

eGFR from serum creatinine level

OTHER

Semi structured interview

Semi structured interview to explore patient experiences. Purposive sampling will be used to explore a wide range of perspectives and transcripts will be analysed using thematic analysis to develop codes and themes.

OTHER

Participatory workshop

Group workshop using qualitative methods. Purposive sampling will be used to explore a wide range of perspectives and transcripts will be analysed using thematic analysis to develop codes and themes. These will be used to develop consensus recommendations.

DIAGNOSTIC_TEST

Metagenome analysis

Analysis of the metagenome using faecal samples of participants after acute kidney injury

DIAGNOSTIC_TEST

Bioimpedance analysis

Estimation of body composition

OTHER

Patient reported outcome measures

EQ-5D-5L, KSQ, WHO-DAS 2.0, K10

OTHER

Measurement of physical performance

Hand grip, Short physical performance battery

Locations (1)

University Hospitals of Derby and Burton NHS Foundation Trust

Derby, Derbyshire, United Kingdom