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Exososmes in Atrophic Scars Management
Sponsor: Zagazig University
Summary
Lay Summary (Simple Explanation) Atrophic scars are depressed scars that form when the skin does not heal properly, commonly seen after acne or injuries. These scars can affect appearance and confidence, and current treatments may not always give satisfactory results. This study aims to evaluate a new treatment using exosomes, which are tiny particles naturally released by cells that help in skin repair and regeneration. Researchers will compare the effect of injecting exosomes directly into scars versus injecting a simple saltwater solution (saline), which serves as a control. Participants will be randomly assigned to receive either exosome injections or saline injections. Neither the patient nor the evaluator may know which treatment is given, to ensure fair comparison. The goal is to determine whether exosomes can safely and effectively improve the appearance and texture of atrophic scars.
Official title: Evaluation of Intralesional Exosomes Versus Intralesional Saline in The Treatment of Atrophic Scars: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2025-06-15
Completion Date
2027-02
Last Updated
2026-05-06
Healthy Volunteers
No
Conditions
Interventions
Intralesional exosomes
exosomes are injected within the substance of the scar.
Intralesional Saline
all patients will receive both, exosomes and saline, each injected into one scar.
Locations (1)
Zagazig University Hospitals
Zagazig, Zagazig, Egypt