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RECRUITING
NCT07569666
NA

Exososmes in Atrophic Scars Management

Sponsor: Zagazig University

View on ClinicalTrials.gov

Summary

Lay Summary (Simple Explanation) Atrophic scars are depressed scars that form when the skin does not heal properly, commonly seen after acne or injuries. These scars can affect appearance and confidence, and current treatments may not always give satisfactory results. This study aims to evaluate a new treatment using exosomes, which are tiny particles naturally released by cells that help in skin repair and regeneration. Researchers will compare the effect of injecting exosomes directly into scars versus injecting a simple saltwater solution (saline), which serves as a control. Participants will be randomly assigned to receive either exosome injections or saline injections. Neither the patient nor the evaluator may know which treatment is given, to ensure fair comparison. The goal is to determine whether exosomes can safely and effectively improve the appearance and texture of atrophic scars.

Official title: Evaluation of Intralesional Exosomes Versus Intralesional Saline in The Treatment of Atrophic Scars: A Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

12

Start Date

2025-06-15

Completion Date

2027-02

Last Updated

2026-05-06

Healthy Volunteers

No

Conditions

Interventions

OTHER

Intralesional exosomes

exosomes are injected within the substance of the scar.

OTHER

Intralesional Saline

all patients will receive both, exosomes and saline, each injected into one scar.

Locations (1)

Zagazig University Hospitals

Zagazig, Zagazig, Egypt