Clinical Research Directory

Inclusion Criteria: * Provide voluntary, signed, and dated informed consent. * Female, aged 35 to 55 years, inclusive. * Currently experiencing perimenopausal symptoms, such as hot flashes, mood changes, sleep disturbance, or irregular cycles. * In generally good health as determined by self-reported medical history. * Agree to maintain existing diet, exercise, and lifestyle patterns throughout the study period. * Able and willing to comply with all study procedures, including electronic consent, app-based data entry, and study questionnaires. * Participants selected for the microbiome substudy must be willing to complete stool and vaginal sample collection. * Females of childbearing potential must agree to use a medically acceptable form of birth control during the study. * Agree to refrain from taking other probiotic, prebiotic, postbiotic, hormonal, or menopause-support supplements during the study. * Have reliable internet or smartphone access. Exclusion Criteria: * Currently pregnant, planning to become pregnant, or breastfeeding. * History or current diagnosis of gynecologic disorders or other conditions affecting hormonal balance. * Current or recent use of hormone replacement therapy or hormonal medications. * History of unstable or newly diagnosed cardiovascular, hepatic, renal, or significant metabolic disorders. * Known gastrointestinal disease or condition affecting absorption or metabolism. * Known allergy or sensitivity to any ingredient in the study supplement. * Current participation in another clinical study involving an investigational product or device, or participation in such a study within the past 30 days. * Any other medical or psychiatric condition that, in the opinion of the investigator or study team, could interfere with study participation, compliance, or interpretation of study results.