Clinical Research Directory

Inclusion Criteria * 21 - 70 years of age * Biological male or female * AHI between 15 - 50 events/hour * Current or new OSA diagnosis * Established or new (within 1 month) CPAP therapy Exclusion Criteria * BMI \> 35 kg/m2 * Diagnosed psychiatric disorders * Hypotension * History of seizures * History of substance abuse or recreational drug use or positive urine drug screen * History of uncontrolled disease including: * Cardiovascular * Pulmonary * Gastrointestinal * Pancreatic * Hepatic * Renal * Hematological * Endocrine (including Type I Diabetes) * Neurological * Urological * Pregnant or breastfeeding * Use of certain antimicrobial, chemotherapeutic, anticoagulant, hypoglycemic, anti-inflammatory, psychotropic, and antihistamine drugs * Prescribed CYP2C9 and/or CYP3A4 inhibitors * Severe OSA that in the investigator's judgment should only begin CPAP treatment * Prior upper airway surgery for snoring or OSA as an adult * Significant defect in nasal patency due to anatomical abnormality or uncontrolled rhinitis * Bariatric surgery within 2 years * Medically managed weight-loss program within 6 months * Noninvasive treatment for OSA within 1 month (self-report) * History of shift work or rotating shifts within 1 month