Clinical Research Directory

Inclusion Criteria: 1. Age 18-45 2. Diagnosis of OCD defined by DSM-V criteria with problematic symptoms in the 12 months following childbirth 3. YBOCS ≥16 4. Either currently taking OCD medications at a stable dose for 8 weeks or unmedicated 5. Concurrent psychotherapy (exposure and response prevention therapy) will be allowed if it was initiated 8 weeks or more before study entry and continues regularly throughout the trial 6. Ability to read, write and understand English sufficiently well to complete study procedures and provide informed consent. Exclusion Criteria: 1. Past history of a primary psychotic or bipolar disorder 2. Current acute suicidality or significantly elevated risk of suicide as determined by the investigators 3. Personal history of moderate traumatic brain injury, epilepsy, or other clinically significant neurological illness except tic disorders 4. A history of pre-eclampsia during the most recent pregnancy if the patient is less than 8 weeks postpartum 5. Current, moderate to severe alcohol or illicit substance use disorder in the last 3 months, determined by clinical assessment 6. Women who are currently pregnant. All participants will be asked to use a reasonable birth control method throughout the study period (barrier, oral contraceptives, etc.). We will not administer pregnancy tests. 7. current psychotic symptoms 8. A current seizure disorder 9. active severe major depressive episode as indicated on the Edinburgh Postnatal Depression Scale (greater than or equal to 19).