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COMPLETED
NCT07571265
NA

Intra-articular Injection for the Relief of Temporomandibular Joint Pain

Sponsor: Cairo University

View on ClinicalTrials.gov

Summary

Which is more effective in the treatment of nonspecific temporomandibular osteoarthritis: platelet-rich plasma (PRP), hyaluronic acid, or triamcinolone acetonide?

Official title: A Comparative Study on the Impact of Intra-articular Injections of Hyaluronic Acid, Platelet-rich Plasma and Triamcinolone Acetonide on the Relief of Temporomandibular Joint Pain

Key Details

Gender

All

Age Range

18 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

64

Start Date

2024-05-01

Completion Date

2025-10-25

Last Updated

2026-05-06

Healthy Volunteers

Yes

Interventions

OTHER

platelet rich plasma and triamcinolone acetonide and hyaluronic acid and saline intra articular injection

* An 18-gauge needle of a 10 ml plastic syringe loaded with normal saline solution will be inserted into the superior joint compartment (SJC). The injection-ejection process was repeated 10 times. Then the SJC will be injected with 1 ml of PRP in group I, 1 ml of triamcinolone acetonide 40 mg/ml in group II, 1 ml of hyaluronic acid (Hyalgan 20 mg/2 ml) in group III, or 1 ml of normal saline in group IV. * Patients will be evaluated after one week and 1 month, then at 3 months and 6 months.

Locations (1)

Faculty of Dentistry

Al Manyal, Cairo Governorate, Egypt