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NOT YET RECRUITING
NCT07572019
PHASE2/PHASE3

Ultrasound Guided Erectror Spinae Block Versus Intracavitary During Medical Thoracoscopy

Sponsor: Kafrelsheikh University

View on ClinicalTrials.gov

Summary

The primary aim: is to compare the effect of US guided ESP block at two levels versus intracavitary blockade in medical thoracoscopy on total peri-procedural (intraoperative and post-operative 12 hours) nalbuphine consumption (mg) during medical thoracoscopy. Secondary aims: Time to first rescue analgesia, postoperative VAS, haemodynamics, recovery time (Aldert \> 9), and adverse events

Official title: Ultrasound-Guided Erector Spinae Plane Block Versus Intracavitary Local Anaesthesia for Peri-procedural Analgesia During Medical Thoracoscopy: A Randomized Control Trial

Key Details

Gender

All

Age Range

25 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2026-05-15

Completion Date

2026-07-20

Last Updated

2026-05-12

Healthy Volunteers

No

Conditions

Interventions

PROCEDURE

ultrasound-guided erector spinae plane block in medical pleuroscopy

On the lateral decubitus position, under full aseptic technique; a high frequency (5-13 MHz) linear probe (or curvilinear in obese patients) of ultrasound covered sterilely will be placed in a parasagittal longitudinal orientation approximately 3 cm lateral to the spinous process to identify the trapezius, rhomboid major (if present), erector spinae muscle and thehyperechoic transverse process with its acoustic shadow, with the target being the fascial plane deep to the erector spinae muscle and superficial to the transverse process; the needle will be inserted in-plane in a cranial-to-caudal direction under real-time ultrasound guidance until it contacts the transverse process, after which 1-3 ml of normal saline is injected to confirm correct plane by lifting the erector spinae muscle off the transverse process, then following negative aspiration 20 ml of 0.25% bupivacaine at each level (10 ml 0.5% bupivacaine + 10 ml normal saline ) will be injected incrementally

PROCEDURE

Intracavitary anaesthesia ICA

After skin infiltration with lidocaine 2%, at the entry point of the trocar, small (2-4 cm) skin incision in the chest wall will be done, A trocar will be introduced into the pleural cavity. If necessary, air is introduced to allow the lung to collapse, creating space to view the pleural surface. The thoracoscope will be inserted to visualize the pleura. The interventional pulmonologist will receive the pre-prepared syringe from the block anaesthetist and will administer the solution intracavitarily via the thoracoscope working channel, without knowledge of its contents. In both groups, a total volume of 40 mL of solution is administered: 20 mL is sprayed over the costal, diaphragmatic, and mediastinal pleura via the thoracoscope working channel, and an additional 20 mL is injected through the chest tube inserted at the end of the procedure , 10-mL normal saline flush, and the chest tube is then clamped for 5 minutes