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NOT YET RECRUITING
NCT07573475
NA

The Effect of tDCS Combined With TMS on Cognitive Impairment and Motor Function After Stroke

Sponsor: Ke Dong, MD

View on ClinicalTrials.gov

Summary

This clinical trial aims to investigate whether transcranial electrical stimulation (tDCS) combined with transcranial magnetic stimulation(TMS) has an impact on the cognitive and motor functions of stroke patients, and to evaluate the safety of this protocol. The main objective is to answer the following question: Can electromagnetic combined stimulation of the left Dorsolateral prefrontal lobe(DLPFC) improve the performance of working memory, motor function and cognitively motor dual tasks in stroke patients? What is its mechanism of action? Participants will undergo a combined real or sham electromagnetic stimulation of 20 minutes of tDCS and 40 seconds of TMS once a day for 7 days. Researchers will compare the effects of real stimulation with sham stimulation to see if the real stimulation can bring better results to patients. Clinical evaluations (cognitive and motor scales) and functional Near-Infrared Spectroscopy(fNIRS) were conducted before and after stimulation to record relevant brain activities

Official title: The Effect of Transcranial Electrical Stimulation Combined With Transcranial Magnetic Stimulation on Cognitive Impairment and Motor Function After Stroke

Key Details

Gender

All

Age Range

30 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

24

Start Date

2026-05-01

Completion Date

2027-05-01

Last Updated

2026-05-11

Healthy Volunteers

No

Interventions

BEHAVIORAL

occupational therapy

occupational therapy 1 hour a day for 7 days

OTHER

real tDCS

real 20 minutes of tDCS once a day for 7 days

OTHER

sham tDCS

sham 20 minutes of tDCS once a day for 7 days

OTHER

real TMS

40 seconds of real TMS once a day for 7 days

OTHER

sham TMS

40 seconds of sham TMS once a day for 7 days

Locations (1)

Department of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China