Clinical Research Directory
Browse clinical research sites, groups, and studies.
International Multi-center Retrospective Study of Patients With Serum Sodium ≤110 mmol/L to Determine the Relationship Between Osmotic Demyelination Syndrome (ODS) and Rapid Correction of Hyponatremia
Sponsor: Rochester General Hospital
Summary
Electronic medical records dating back as far as available for each center to identify patients admitted to the hospital with a serum sodium ≤110 mmol/l. Data on patient demographics, presenting symptoms, vital signs, laboratory findings, treatment given, sodium correction rates, presence of risk factors for osmotic demyelination syndrome (ODS) and outcomes including suspected and MRI-confirmed ODS, in-hospital death, and imaging confirmation of cerebral edema
Official title: Neurological Complications Associated With Serum Sodium ≤110 mmol/L and Its Treatment: An International Multi-Centre Retrospective Study.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
800
Start Date
2023-11-01
Completion Date
2026-06-30
Last Updated
2026-05-08
Healthy Volunteers
No
Interventions
Hypertonic 3% saline
Rapid Correction of hyponatremia
Locations (1)
University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania, United States