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Repetitive GON Blockade for Menstrual Migraine
Sponsor: Saglik Bilimleri Universitesi
Summary
: The primary objective of this prospective, randomized, double-blind, placebo-controlled clinical trial is to evaluate whether repetitive bilateral greater occipital nerve (GON) blockade administered with a local anesthetic (0.5% bupivacaine) significantly reduces headache severity, attack duration, and the number of pain days in female patients with menstrual migraine compared to a placebo group (normal saline). Patients will receive injections twice a month for three months (seven days before the expected onset of menstruation and on the first day of menstruation).
Official title: Perimenstrual Repetitive Greater Occipital Nerve Blockade for Menstrual Migraine: A Randomized, Double-Blind, Placebo-Controlled Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
48
Start Date
2024-10-19
Completion Date
2025-11-30
Last Updated
2026-05-08
Healthy Volunteers
No
Interventions
0.5% bupivacaine
Bilateral greater occipital nerve (GON) blockade using a local anesthetic.
Normal Saline
Bilateral greater occipital nerve (GON) blockade using placebo (normal saline).
Locations (1)
Saglik Bilimleri Universitesi
Istanbul, Istanbul, Turkey (Türkiye)