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Histidine Supplementation for Antitumor Immunity in Colorectal Cancer
Sponsor: Jing-yuan Fang, MD, Ph. D
Summary
The goal of this clinical study is to learn whether oral histidine supplementation may be safely used to support antitumor immune function during standard colorectal cancer treatment. Participants with colorectal cancer in the supplementation group will: Take 2g oral histidine once daily during standard colorectal cancer treatment; Provide blood samples before and after supplementation; Attend regular follow-up visits for laboratory tests, safety assessment, and treatment evaluation.
Official title: A Single-arm Clinical Study of Histidine Supplementation for Antitumor Immunity in Colorectal Cancer
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-05-06
Completion Date
2027-06
Last Updated
2026-08-20
Healthy Volunteers
No
Conditions
Interventions
Histidine
Histidine capsules, 1000 mg per capsule, taken orally as 2 capsules once daily for 9 weeks. Histidine supplementation will be administered in addition to standard anti-tumor treatment determined by the treating physician according to clinical guidelines.
Locations (1)
Shanghai Punan Hospital of Pudong New District
Shanghai, Shanghai Municipality, China