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NOT YET RECRUITING
NCT07579910
PHASE3

Intracerebroventricular Tralesinidase Alfa in Children With Mucopolysaccharidosis Type IIIB

Sponsor: Spruce Biosciences

View on ClinicalTrials.gov

Summary

The primary objectives of this study are to evaluate the effects of Tralesinidase Alfa (TA) on cognition

Official title: A Phase 3, Randomized, Single-blind, Parallel Group, Controlled, Multicenter Study to Evaluate the Safety, Tolerability, and Efficacy of Intracerebroventricular Tralesinidase Alfa Treatment Compared to Standard of Care in Mucopolysaccharidosis Type IIIB (MPS IIIB, Sanfilippo Syndrome Type B)

Key Details

Gender

All

Age Range

1 Year - 5 Years

Study Type

INTERVENTIONAL

Enrollment

14

Start Date

2026-12

Completion Date

2033-08

Last Updated

2026-05-12

Healthy Volunteers

No

Conditions

Interventions

DRUG

Tralesinidase alfa (TA)

TA study drug is a sterile solution for ICV infusion.