Clinical Research Directory

Inclusion Criteria: 1. Signed patient informed consent form (ICF). 2. Females aged ≥ 30 years and ≤ 55 years at baseline with no desire to conceive, with or without simple endometrial hyperplasia (without atypia). 3. Diagnosis of AUB. 4. Premenopausal (follicle-stimulating hormone level ≤ 40 mIU/mL), women who don't want to receive hormonal treatment or who have failed to respond to hormonal treatment. 5. Pictorial Blood Loss Assessment Chart (PBAC) score ≥150 at baseline. 6. Normal endometrial biopsy. 7. Negative PAP test. 8. Willingness to follow all study procedures, including attending all site visits, tests, and examinations. Exclusion Criteria: 1. BMI ≥35 2. Postmenopausal status. 3. Undiagnosed vaginal bleeding. 4. A patient with a history of a prior completed endometrial ablation procedure and/or endometrial resection (including endometrial ablation/resection performed immediately prior to the ATTTVAS Ablation Treatment) regardless of the modality by which it was performed. 5. Previous uterine surgery. 6. Not willing to avoid the use of vaginal ring, hormonal intrauterine device (concomitant IUD such as Essure is not allowed prior to the ATTTVAS Ablation Treatment), oral contraceptives during the study period. 7. Pregnant or breastfeeding. 8. Less than 1-year post-partum. 9. Any contraindication to endometrial ablation. 10. History of previous classical cesarean section or transmural myomectomy, including hysteroscopic and/or laparoscopic myomectomy performed immediately prior to the ATTTVAS Ablation Treatment. 11. Confirmed pelvic inflammatory disease, active/acute endometritis, sexually transmitted disease, bacteremia, sepsis, other active local and/or systemic infection. 12. Active genital or urinary tract infection (e.g., cervicitis, vaginitis, endometritis, salpingitis or cystitis) at the time of treatment. 13. Congenital malformations of the female genital tract. 14. Subjects with suspected or known coagulopathies or receiving anticoagulation therapy. 15. A patient currently on medications that could thin the myometrial muscle, such as long-term steroid use (except for inhaler or nasal therapy for asthma). 16. Documented cervical dysplasia, complex or atypical endometrial hyperplasia, abdominal or pelvic cancer. 17. Presence of any relevant severe condition or clinically relevant abnormal laboratory parameters that in the opinion of the Investigator may interfere with the participation to the study. 18. Presence of any relevant severe organic, systemic, or metabolic disease (particularly significant history of cardiac, renal, neurological, psychiatric, oncology, endocrinology, metabolic or hepatic disease), or abnormal laboratory values that will be deemed clinically significant in Investigator's opinion. 19. Active malignant neoplasm of any type, or history of a malignancy (patients with a history of other malignancies that have been surgically removed and who have no evidence of recurrence for at least five years before study enrollment are also acceptable). 20. Participation in another investigational study within the previous 30 days. 21. Recent history or suspicion of alcohol abuse or drug addiction. 22. Inability to follow study procedures. 23. History of allergic reactions to propofol and/or fentanyl.