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Eccentric Exercise, Muscle Damage, and Oxygen Uptake Across Menstrual Cycle Phases
Sponsor: National and Kapodistrian University of Athens
Summary
The existing literature examining the effect of female sex hormones across the phases of the menstrual cycle on muscle microdamage and oxygen uptake is limited. The protective role of estrogens against muscle microdamage is supported by findings from some studies; however, it is questioned by others. The aim of the present study was to investigate the effect of eccentric exercise on biomarkers of muscle microdamage and on oxygen uptake during two phases of the menstrual cycle in healthy premenopausal women.
Official title: The Effect of Eccentric Exercise on Biomarkers of Exercise Induced Muscle Damage and Oxygen Uptake: Differences Between Phases of the Menstrual Cycle
Key Details
Gender
FEMALE
Age Range
18 Years - 28 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2025-05-15
Completion Date
2026-01-22
Last Updated
2026-05-12
Healthy Volunteers
Yes
Interventions
Isokinetic eccentric exercise using knee extensors of the right lower limb
Isokinetic eccentric exercise consisted of 10 min at 40% of maximal voluntary contractions, followed by 2 min maximal intensity muscle effort
Isokinetic eccentric exercise using knee extensors of the left lower limb
Isokinetic eccentric exercise consisted of 10 min at 40% of maximal voluntary contractions, followed by 2 min maximal intensity muscle effort
Locations (1)
Department of Physical Educaiton and Sport Science
Dafni, Attica, Greece