Clinical Research Directory

Inclusion Criteria: * Male or female aged 18 + years of age * Admission to the Surgical Intensive Care Unit in the Northwell Health hospital system * Moderate to severe acute pancreatitis based on Atlanta criteria * Inability to tolerate ≥75% of goal EN (25 kcal/kg/d) Exclusion Criteria: * Moribund patients expected to expire within 120 hours * Evidence of unresolved intestinal obstruction, ischemia, bleeding, perforation, fistulas or tract discontinuity, or other contraindication for enteral nutrition * Diagnosis or evidence of C. Difficile or other gastrointestinal infection that may manifest with diarrhea * Pre-existing constipation defined as laxative or stool softener use prior to admission to the hospital * Patients receiving cancer-related treatment in the last 3 months * History of cystic fibrosis * Any other reason that the treating or investigator team considers to be a contraindication to enteral nutrition