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An Exploratory Study of Personalized Cancer Vaccine in Adjuvant Therapy of Solid Tumors
Sponsor: Suzhou Abogen Biosciences Co., Ltd.
Summary
The purpose of this study is to evaluate the safety and tolerability of ABO2109 in combination with toripalimab, and to evaluate the immunogenicity, pharmacokinetics, pharmacodynamics, as well as biomarker characteristics of the investigational cancer vaccine. In addition, the antitumor activity of ABO2109 will be assessed during both dose exploration and expansion stages, the accumulative data will support the clinical development of ABO2109.
Official title: An Exploratory Study of Personalized Cancer Vaccine (ABO2109) in Adjuvant Therapy of Solid Tumors
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-04-17
Completion Date
2031-04-17
Last Updated
2026-05-13
Healthy Volunteers
No
Conditions
Interventions
ABO2109 Injection;Toripalimab
Drug: ABO2109 Injection personalized cancer vaccine Drug: Toripalimab Anti-PD-1 monoclonal antibody
ABO2109 Injection;Toripalimab
Drug: ABO2109 Injection personalized cancer vaccine Drug: Toripalimab Anti-PD-1 monoclonal antibody