Clinical Research Directory

Inclusion Criteria: * Signed informed consent before the study and understood the study content, procedures, and possible adverse reactions. * Healthy adult man aged 20 to 48 years, inclusive. * Normal social drinking lifestyle and no alcohol dependence. * Aspartate aminotransferase and alanine aminotransferase values within two standard deviations of the normal range. * Able to maintain normal healthy routines during the study. * Able to avoid other interfering supplements for 2 weeks before and during the study. * Abstained from alcohol for 24 hours before the study. * Abstained from caffeinated beverages, including coffee, tea, and energy drinks, for 12 hours before the study. Exclusion Criteria: * Known allergy or hypersensitivity to product ingredients, including magnolia bark, milk thistle extract, turmeric, or alcohol. * History of multiple drug or food allergies. * Acute or chronic inflammatory disease, including influenza A, within the previous month. * Hypertension. * Participation in any other clinical trial within 1 month before first use of the study product. * Clinically significant gastrointestinal, renal, hepatic, neurologic, hematologic, endocrine, oncologic, pulmonary, immune, psychiatric, cardiovascular, cerebrovascular, or metabolic disease within the previous 6 months. * Acute illness or concomitant medication use from screening to first use of the study product. * Surgery within the previous 3 months. * Blood donation or major blood loss greater than 450 mL within the previous 3 months. * Difficulty swallowing. * Use of prescription or non-prescription medications affecting nutritional supplements or alcohol metabolism. * Any other factor judged by the investigator to make participation inappropriate.