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ENROLLING BY INVITATION
NCT07589751
NA

Biomaterials Exposed to Oral Environment: Which One is the Appropriate Option?

Sponsor: Pontificia Universidade Católica do Rio Grande do Sul

View on ClinicalTrials.gov

Summary

After tooth extraction, bone loss can compromise future dental implant treatment. Dentists often use biomaterials to preserve bone, but in many cases these materials are left exposed to the oral environment, where saliva and bacteria may affect healing. This study will investigate how different collagen-based biomaterials behave when exposed in the mouth, evaluating healing, bone changes, bacterial contamination, and patient experience. Sixty patients will be included in a randomized clinical trial comparing two commonly used biomaterials and natural healing. The results will help clinicians choose safer and more effective treatments, improving outcomes for patients undergoing tooth extraction and future implant rehabilitation.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2026-05-05

Completion Date

2027-12

Last Updated

2026-09-17

Healthy Volunteers

Yes

Interventions

PROCEDURE

Alveolar Ridge Reconstruction

Alveolar ridge preservation (ARP) using Bio-Oss Collagen® + Bio-Gide® exposed to the oral environment.

PROCEDURE

Alveolar Ridge Reconstruction

ARP using Bio-Oss Collagen® + Mucograft® Seal® exposed to the oral environment.

Locations (1)

PUCRS

Porto Alegre, Rio Grande do Sul, Brazil