Clinical Research Directory

Validation of the PRST Score Against Bispectral Index

Sponsor: Gadjah Mada University

Summary

The goal of this randomized controlled trial is to evaluate whether the PRST (Evans) score is a valid method for monitoring the depth of general anesthesia in adult surgical patients. It will also assess whether combining the PRST score with Bispectral Index (BIS) monitoring improves anesthetic depth assessment compared with PRST-guided monitoring alone. The main questions it aims to answer are: 1. Does the PRST score correlate with BIS values during general anesthesia? 2. Does visible BIS-guided monitoring improve anesthetic depth assessment compared with PRST-guided monitoring alone? Researchers will compare patients managed using PRST-guided monitoring alone with patients managed using PRST plus visible BIS-guided monitoring. Participants will: 1. Undergo elective surgery under general anesthesia 2. Receive intraoperative anesthetic depth monitoring using PRST score alone or PRST combined with BIS monitoring 3. Have PRST score, BIS, heart rate, and blood pressure recorded at predefined intraoperative timepoints 4. Complete a postoperative interview assessing recall, dreaming, and anesthesia-related discomfort

Official title: Validation of the PRST Score Against Bispectral Index During General Anesthesia: A Randomized Controlled Trial

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