Clinical Research Directory

Inclusion Criteria: * Patients with T1DM according to the international society of pediatric and adolescent diabetes (ISPAD). (Couper et al., ISPAD 2022). * Age 10- 18 years old. * Diabetic nephropathy according to ISPAD. (Couper et al., ISPAD 2022). * eGFR \> 30 ml/min per 1.73 m2 Exclusion Criteria: * Patient with other types of diabetes e.g. T2DM, maturity onset diabetes of the young (MODY). * Presence of contraindication for empagliflozin e.g. History of serious hypersensitivity reaction to empagliflozin, end-stage renal disease, or dialysis. * Other types of nephropathy.