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Enucleation Ratio as a Novel Predictor of Symptomatic Improvement After HoLEP
Sponsor: Ondokuz Mayıs University
Summary
The goal of this observational study is to determine whether the rate of prostate tissue removed during surgery relative to the preoperative total prostate volume (referred to as the "enucleation ratio") predicts symptomatic improvement 3 months after HoLEP. The main question it aims to answer is: \- What is the minimum enucleation ratio required to achieve clinically important symptomatic improvement? (Symptomatic improvement is referred to as a threshold of having an International Prostate Symptom Score (IPSS) lower than 8 points, which is determined by the American Urological Association (AUA) and European Association of Urology(EAU)).
Official title: Predictive Value of Enucleation Ratio for Symptomatic Improvement After HoLEP: A Multicenter Prospective Cohort Study
Key Details
Gender
MALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
400
Start Date
2026-07-01
Completion Date
2027-03-30
Last Updated
2026-05-19
Healthy Volunteers
No
Conditions
Interventions
Holmium laser enucleation of prostate (HoLEP)
HoLEP is a widespread and minimally invasive surgical method to treat LUTS caused by BPO. En-bloc or tri-lobar technique will be performed according to the surgeon's preference during the procedure.
Locations (1)
Ondokuz Mayis University, Faculty of Medicine, Department of Urology
Samsun, Turkey (Türkiye)