Clinical Research Directory
Browse clinical research sites, groups, and studies.
CRISTEL Study: Monitoring of Pregnancies in Women After Solid Organ Transplantation
Sponsor: Hopital Foch
Summary
The objective of this research is to obtain standardized and independent data on the number of pregnancies occurring in France and their follow-up up to 1 year postpartum (or post-pregnancy termination). This study will then aim to describe the clinical characteristics and maternal and perinatal outcomes of pregnancies in this specific population. These data will enable the dissemination of clear and up-to-date information to the medical community, thus contributing to better patient counseling and, more broadly, to couples. They will also serve to issue recommendations to optimize the planning and follow-up of pregnancies in women with solid organ transplants. Finally, this initiative aims to promote clinical research on pregnancies.
Key Details
Gender
FEMALE
Age Range
18 Years - 48 Years
Study Type
INTERVENTIONAL
Enrollment
2000
Start Date
2026-09-01
Completion Date
2036-09-01
Last Updated
2026-05-18
Healthy Volunteers
No
Interventions
Blood sample
Two optional (non-mandatory) biological samples may be collected as part of this study: A 2 mL venous blood sample may be taken during a routine prenatal follow-up visit (around 30 weeks of gestation) in order to analyze the preeclampsia biomarker (sFlt-1/PlGF ratio), whenever preeclampsia is suspected. A 5 mL sample from cord blood may be collected after delivery to analyze, in the newborn, the complete blood count, white blood cell differential, lymphocyte phenotyping (T CD3+, CD19+CD20+, and NK CD46+), and immunoglobulin levels (G, A, and M for humoral immunity, and E for allergy-related function).