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Repeated Injections of Adipose-derived Stem Cells in Rotator Cuff Tears
Sponsor: University of Southern Denmark
Summary
The aim of the project is to investigate whether repeated implantations of micro-fragmented adipose tissue (MFAT), into the shoulder muscle can improve the outcome of standard surgical treatment for rotator cuff tears (RCT). The investigators hypothesize that combining surgery with repeated implantations of micro-fragmented adipose tissue (MFAT) into the muscle provides a more effective treatment for patients with rotator cuff tears compared to standard surgical treatment. The result would be better outcomes such as improved shoulder functioning and reduced pain.
Official title: Effects and Benefits of Repeated Injections of Adipose-derived Stem Cells on Shoulder Function in Rotator Cuff Tears: A Randomized Controlled Study
Key Details
Gender
All
Age Range
30 Years - 69 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-10
Completion Date
2028-08
Last Updated
2026-09-30
Healthy Volunteers
No
Interventions
Adipose derived stem cell injection
A total of 5 mL of the stem cell suspension is injected into the supraspinatus muscle at three predefined sites located at the musculotendinous junction. For each site, 1.5-2.0 mL of the suspension is administered using an 18-gauge syringe. Adipose derived stem cell injections for the triple injection will be repeated at 4 and 8 weeks postoperatively. These follow-up treatments will be performed in an outpatient clinic.
Placebo
Standard care