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Dietary Intervention and Physical Activity in Patients With Heart Failure and Reduced Ejection Fraction
Sponsor: Medical University of Silesia
Summary
Heart failure with reduced ejection fraction (HFrEF) is frequently associated with abnormalities in body composition, including reduced skeletal muscle mass and sarcopenia, which are independent predictors of reduced exercise tolerance, impaired quality of life, and increased mortality. Despite advances in pharmacological therapy, evidence-based non-pharmacological strategies aimed at preventing muscle mass loss remain limited. This randomized controlled trial aims to evaluate the effects of dietary intervention based on the DASH diet with high-protein elements, resistance exercise training, and their combination on skeletal muscle mass, functional capacity, echocardiographic parameters, biochemical markers, and quality of life in patients with HFrEF.
Key Details
Gender
All
Age Range
30 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2023-05-08
Completion Date
2027-04
Last Updated
2026-05-19
Healthy Volunteers
No
Interventions
Resistance Exercise
The exercise intervention includes resistance training using elastic bands, with instruction and follow-up provided by a medical rehabilitation specialist.
Dietary Intervention
Individualized 14-day meal plan based on the DASH diet with high-protein components.
Locations (1)
2nd Department and Clinical Ward of Cardiology Specialist Hospital in Zabrze, Poland
Zabrze, Silesian Voivodeship, Poland