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Analysis of Different Second Line Treatment in Advanced NSCLC Patients Progressing After 1st Line Immune Checkpoint Inhibitor Therapy
Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Summary
The second-line treatment options in clinical practice for immunotherapy progress are complex. Treatment strategies need to be selected based on different progression patterns. It is difficult to simultaneously explore multiple treatment modalities through previous clinical studies. Observational studies through real-world research can efficiently convert clinical practice data into clinical treatment evidence. This study aims to observe the treatment patterns and clinical outcomes of advanced NSCLC patients who received first-line immunotherapy checkpoint inhibitor treatment after progression, in order to provide guidance for the second-line treatment options for patients with first-line immunotherapy progress.
Official title: Analysis of Different Treatment Modalities and Clinical Outcomes in Advanced NSCLC Patients Progressing After First-Line Immune Checkpoint Inhibitor Therapy: An Observational Study Based on Real-World Data
Key Details
Gender
All
Age Range
1 Year - Any
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2026-07-01
Completion Date
2027-06-30
Last Updated
2026-05-19
Healthy Volunteers
No
Conditions
Interventions
Observation
The patients' second-line treatment received and the follow-up observations were retrospectively collected.
Locations (3)
Cancer Hospirtal, Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China
Cancer Hospirtal, Chinese Academy of Medical Sciences, Shenzhen
Shenzhen, Guangdong, China
Shanxi Provincial Cancer Hospital
Taiyuan, Shanxi, China