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Ketamine Added to Quadratus Lumborum Block for Pain Relief After Infant Pyeloplasty
Sponsor: Alexandria University
Summary
This prospective randomized study evaluates the effect of adding ketamine to bupivacaine in ultrasound-guided quadratus lumborum (QL) block for postoperative pain management in infants undergoing open pyeloplasty. Forty infants aged 0-12 months undergoing elective open pyeloplasty are randomly assigned to receive either QL block with bupivacaine plus ketamine or QL block with bupivacaine alone. Postoperative pain is assessed using the CRIES pain scale. Additional outcomes include duration of analgesia, rescue opioid requirements, total opioid consumption, length of hospital stay, and occurrence of complications.
Official title: Ketamine As Adjuvant to Bupivacaine in Ultrasound Guided Quadratus Lumborum Block for Infants Undergoing Open Pyeloplasty
Key Details
Gender
All
Age Range
Any - 12 Months
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2025-06-01
Completion Date
2026-02-01
Last Updated
2026-05-19
Healthy Volunteers
No
Interventions
Ketamine + Bupivacaine
Ketamine hydrochloride (1 mg/kg) added to bupivacaine 0.25% (0.5 mL/kg) administered by ultrasound-guided quadratus lumborum block during open pyeloplasty.
Bupivacaine
Bupivacaine 0.25% (0.5 mL/kg) administered by ultrasound-guided quadratus lumborum block during open pyeloplasty.
Locations (1)
Alexandria University
Alexandria, Egypt