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DYnamic decisioN Support for IntegrAting PrEP in Clinics for Young People in Alabama and Botswana
Sponsor: University of Alabama at Birmingham
Summary
This study evaluates strategies to improve access to HIV prevention through the integration of pre-exposure prophylaxis (PrEP) into existing healthcare settings, rather than limiting delivery to specialty clinics. The study addresses barriers to PrEP uptake, including limited awareness, stigma, and restricted access, and recognizes that availability alone may not ensure initiation or sustained use. The study includes two components. First, a longitudinal cohort of current PrEP users will be followed to assess changes in access, preferences, and PrEP use over time in real-world settings. Second, a dynamic decision-support toolkit will be developed and evaluated to support patients and providers in PrEP-related decision-making. The toolkit will include patient- and provider-facing components to support clinical decision-making, improve risk understanding, and facilitate integration of PrEP into routine healthcare. The toolkit will be refined and beta-tested in selected healthcare facilities in Botswana and Alabama.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1000
Start Date
2026-06
Completion Date
2031-12
Last Updated
2026-06-25
Healthy Volunteers
Yes
Conditions
Interventions
Observational cohort (PrEP use in real-world settings)
No intervention
Locations (1)
Princess Marina Hospital
Bontleng, Gaborone, Botswana