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Lifestyle Intervention to Improve Muscle Function in Older Adults
Sponsor: Pennington Biomedical Research Center
Summary
The goal of this randomized controlled two-arm trial is to determine the effect of a diet and exercise intervention for 12 weeks on body composition, muscle function, and energy balance in 80 adults aged 50 years and over with obesity and insulin resistance. The main questions the trial aims to answer are: Will 12 weeks of a structured nutrition plan + exercise reduce fat mass, improve muscle function, and increase energy deficit compared to the usual diet + exercise. The hypothesis is that 12 weeks of a structured nutrition plan + exercise will reduce fat mass, improve muscle function, and produce greater energy deficit than the usual diet + exercise. Participants will be provided with all meals for 12 weeks and will exercise at the Center under supervision three times each week. Pre and post-intervention, body composition, physical function, and energy deficit will be measured.
Key Details
Gender
All
Age Range
50 Years - Any
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2026-07-20
Completion Date
2030-12
Last Updated
2026-09-03
Healthy Volunteers
No
Interventions
Structured nutrition plan
Participants will receive a structured nutrition plan.
Typical or usual diet
Participants will receive a diet representing the usual diet in this population.
Supervised Exercise
Participants will complete aerobic and resistance training under supervision three times per week.
Locations (1)
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States