Clinical Research Directory

Inclusion Criteria: * 18+ years old * Have an established diagnosis of Prediabetes or Type 2 diabetes * Have a glycated hemoglobin (HbA1c) below 8% (64 mmol/mol) and a body mass index (BMI) between 18-40 kg/m2 that will be determined from your height and weight * Are willing to use an Abbott FreeStyle Libre 3/3+ Continuous Glucose Monitor (CGM) supplied by the study and provide the study investigators access to the CGM data * Are willing to use the study wearable devices (e.g., Oura Ring) * Are able to read, write, and speak in English * If you use long-acting insulin, you must be on a prescribed regimen where you administer it at bedtime only and no other time of day (bolus short-acting may be used at any time as needed) * All medication regimens must have a minimum of 30 days supply, and no new medications started within 30 days of enrollment * Weight must be stable (± 10 pounds) for 2 months prior to enrollment * Must have a personally owned iPhone 6s or newer (iOS 16.4+) or Android smartphone (version 12 or newer) and use this phone to download and use the study app and use the provided study devices * Must have a personally owned computer or tablet or have access to these devices at home * Must reside in the North San Francisco Bay area and be willing to travel to Novato, CA to attend two morning clinic assessments at the Buck Institute Exclusion Criteria: * Using any Abbott CGM (prescribed or OTC) * BMI \<18 kg/m2 or \>40 kg/m2 * Dairy or soy allergy * Currently pregnant or breastfeeding * Diagnosed with Type 1 diabetes or MODY (Maturity-Onset Diabetes of the Young) * Using an insulin pump * Using any of the following medications: Glucocorticoids, Non-Selective Beta Blockers (e.g., propranolol), Thiazide Diuretics * Currently using tobacco products (cigarettes, vapes, chew, dip, etc.) * Hospitalized overnight for any reason in the last 3 months * History of pancreatic disease (other than diabetes) or pancreatic transplantation * Have any active malignancy within the last 12 months * History of bariatric / other gastrointestinal surgery anticipated to affect glucose metabolism / cause gastroparesis * History of systemic disease (hepatic, cardiovascular, other) likely to interfere with glucose metabolism or study participation