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Dexmedetomidine vs Propofol-lidocaine Mixture in Preventing the Post Operative Emergence Agitation Following Sevoflurane Anasthesia
Sponsor: Sohag University
Summary
Primary we will Compare the Efficacy between Dexmedetomidine and "Propofol-lidocaine" mixture in preventing the post operative emergence agitation following sevoflurane anasthesia in pediatric ophthalmic surgeries Secondary we will evaluate time of extubation, time of orientation, Hemodynamic variables, Visual analog scale ( VAS), facial expressions scale , Adverse events
Official title: The Efficacy of Dexmedetomidine Versus Propofol-lidocaine Mixture in Preventing the Post Operative Emergence Agitation Following Sevoflurane Anesthesia in Pediatric Ophthalmic Surgeries , A Prospective Randomized Comparative Controlled Study
Key Details
Gender
All
Age Range
2 Years - 8 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2026-05-01
Completion Date
2026-12
Last Updated
2026-05-22
Healthy Volunteers
Yes
Conditions
Interventions
Dexmedetomidine
Dexmedetomidine 0.3mcg /kg over diluted in 10 ml 0.9% Na cl over 10 min and 10 min before end of surgery
Propofol
Propofol 2mg/kg plus lidocaine 1mg/kg over 10 min and 10 min before end of surgery.
Placebo
receive placebo 10 ml 0.9% Nacl over 10 min and 10 min before end of surgery