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Quantitative Chest CT and Multi-Omics to Distinguish Asthma From COPD and Predict Treatment Response
Sponsor: Korea University Guro Hospital
Summary
This study aims to improve the diagnosis and treatment prediction of asthma and chronic obstructive pulmonary disease (COPD) by combining quantitative chest computed tomography (CT) imaging with multi-omics data. Adults with asthma or COPD will be enrolled and undergo routine clinical evaluations, pulmonary function tests, blood tests, and chest CT scans. Additional samples, such as sputum and microbiome specimens, may also be collected. No experimental drugs or devices will be administered as part of this study. Researchers will analyze CT imaging features together with clinical, laboratory, and biological data to better distinguish asthma from COPD and to identify factors that may predict treatment response. The findings are expected to contribute to more precise and personalized management of chronic airway diseases.
Official title: Prospective Multicenter Cohort to Discriminate Asthma Versus Chronic Obstructive Pulmonary Disease and Predict Treatment Response Using Quantitative Chest CT and Multi-Omics
Key Details
Gender
All
Age Range
19 Years - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2025-12-22
Completion Date
2027-12-22
Last Updated
2026-07-07
Healthy Volunteers
No
Locations (2)
SMG-SNU Boramae Medical Center
Seoul, Dongjak-gu, South Korea
Korea University Guro Hospital
Seoul, Guro-gu, South Korea