Clinical Research Directory
Browse clinical research sites, groups, and studies.
Genetic Markers Associated With Capsaicinoid Supplementation Effects in Overweight and Obesity
Sponsor: Universidad Autonoma de Baja California
Summary
Capsaicinoids, compounds found in chili peppers of the genus Capsicum, are responsible for their spiciness and may have potential benefits in weight control and cardiometabolic health. They act on processes such as appetite regulation, fat burning, inflammation, and metabolism, although their effects vary among individuals, possibly due to genetic factors. In Mexico, where chili consumption is high and obesity is a significant public health problem, it is particularly relevant to study these genetic variations. The proposed research aims to identify genetic markers that can predict the response to capsaicinoid supplementation and thus develop personalized nutritional strategies for the treatment of obesity and its complications.
Official title: Identification of Genetic Markers Associated With the Effects of Capsaicinoid Supplementation on Appetite, Body Composition, Metabolic Profile, and Inflammatory Markers in Individuals With Overweight or Obesity
Key Details
Gender
All
Age Range
25 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2026-04-22
Completion Date
2026-11-23
Last Updated
2026-05-22
Healthy Volunteers
No
Conditions
Interventions
Capsipro supplementation
This intervention differs from similar studies due to the use of standardized capsaicin in fixed-dose capsules, rather than chili extracts, whole foods, or non-standardized mixtures. It is also distinguished by a continuous daily administration regimen over 16 weeks, which allows the assessment of sustained effects over time on anthropometric and metabolic parameters under controlled conditions.
Corn starch placebo
Capsules indistinguishable from Capsipro, composed of corn starch, administered twice daily for 16 weeks
Locations (1)
Universidad Autónoma de Baja California
Tijuana, Estado de Baja California, Mexico