Clinical Research Directory

Inclusion Criteria: * Adult age 18 or older * Health status of American Society of Anesthesiologists (ASA) class 1 or 2 * Able to provide informed consent * Able to appear in person at OMRIC on the days indicated for the study Exclusion Criteria: * ASA class 3 or higher * Pregnant patients * Taking any medication that would affect pain perception or interact with local anesthetic * Allergic/history of adverse reaction to local anesthetic or any component in the local anesthetic * Paresthesia in the area of innervation of Cranial Nerve V3 * Active infection or abscess in the oral and maxillofacial region * History of temporomandibular disorder, maximum incisal opening less than 15mm * History of recent dental trauma (within the past 6 months) * Dental hypersensitivity * Claustrophobia and/or conditions of anxiety or motion disorder (for MRI purposes) * Metallic, electronic, or magnetic implants or devices classified as MR Unsafe or Conditional by the American College of Radiology * Unable to give informed consent