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COMPLETED
NCT07602803

The Effect of GLP1 Agonists on Weight Loss in BBS Cohort in the UK

Sponsor: The Queen Elizabeth Hospital

View on ClinicalTrials.gov

Summary

The goal of this observational study is to learn about the long-term effects of GLP1 agonists (weight loss jab, including Mounjaro) in patients with Bardet-Biedl Syndrome (BBS) who take GLP1 agonists to treat high body weight. The main question: Do GLP1 agonists effectively and safely lower body weight in patients with BBS when taken long-term, compared to patients not on these medications? The investigators look at the change (%) in weight during the observational periods.

Official title: GLP1 Agonists Once Weekly for the Treatment of Obesity in Patients With Bardet-Biedl Syndrome (BBS)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

300

Start Date

2023-01-01

Completion Date

2026-04-22

Last Updated

2026-05-27

Healthy Volunteers

No

Locations (1)

Queen Elizabeth Hospital Birmingham

Birmingham, West Midlands, United Kingdom