Clinical Research Directory

Inclusion Criteria: * Adults aged 25-50 years * Females over 40 years must have had a cycle in the last 6 months * Body mass index (BMI) at least 18.5 and at most 55.0 kg/m2 * Impaired blood glucose by at least one of the following criteria: * Fasting blood glucose at least 100 mg/dL (5.6 mmol/L) and less than 125 mg/dL (6.9 mmol/L) * HbA1c at least 5.7% and less than 6.5% * Willing and able to comply with study foods * Willing and able to ingest acetaminophen as part of study procedures * Able to read, speak, and understand English Exclusion Criteria: * Weight change ≥5% in past 6 months, actively trying to lose weight, or unwilling to remain weight stable throughout the study based on self-report * Recent history within past 12 months of medical provider-diagnosed cardiovascular, renal, or liver disease that required treatment * Current or past diagnosis of cancer (except skin cancer) in the last 5 years * Current or past diagnosis of type 1 or type 2 diabetes * Recent history within past 12 months of medical provider-diagnosed gastrointestinal or neurological disorders if not managed/stable for at least 3 months (with or without treatment) * Recent history within past 12 months of medical provider-diagnosed psychiatric disorders including eating disorders or severe depression if not managed/stable for at least 3 months (with or without treatment) * Food allergies or other reasons preventing consumption of study foods * Any glucose-lowering medication except biguanides (e.g., Metformin) if stable for at least 3 months or incretins (i.e., GLP-1RA-based) if stable for at least 3 months * Current smoking or vaping or history of smoking or vaping in the past 6 months * Binge and/or heavy drinking (i.e., \>3 drinks on any given occasion and/or \>7 drinks/week) * Currently pregnant or planning to become pregnant or breastfeed in the next 3 months by self-report