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Combined Oral and Parenteral Nutritional Therapy After Gastrectomy for Gastric Cancer
Sponsor: Kyo Young Song
Summary
Patients undergoing gastrectomy for gastric cancer frequently experience insufficient oral intake during the postoperative recovery period because of reduced gastric capacity, early satiety, and gastrointestinal symptoms. Although oral nutritional supplements (ONS) are commonly recommended, adherence is often poor, resulting in a postoperative nutritional gap. This prospective randomized clinical trial was designed to evaluate the impact of combined oral and parenteral nutritional therapy on nutritional status and recovery after gastrectomy for gastric cancer. Patients were randomized to either a combined nutritional therapy group receiving oral nutritional supplementation plus parenteral nutrition or a control group receiving standard postoperative care. The primary endpoint was postoperative body weight change at 4 weeks after surgery. Secondary endpoints included body composition, nutritional intake, inflammatory and immune markers, laboratory parameters, and quality of life outcomes.
Official title: Bridging the Postoperative Nutritional Gap After Gastrectomy for Gastric Cancer: A Prospective Randomized Trial of Combined Oral and Parenteral Nutritional Therapy
Key Details
Gender
All
Age Range
20 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
55
Start Date
2020-10-01
Completion Date
2024-05-31
Last Updated
2026-05-22
Healthy Volunteers
No
Conditions
Interventions
Oral Nutritional Supplementation
Patients received oral nutritional supplementation using Encover® three times daily during the postoperative recovery period after gastrectomy for gastric cancer.
Parenteral Nutrition
Supplemental parenteral nutrition was administered during hospitalization and after discharge to support postoperative nutritional requirements.
Standard Postoperative Nutritional Care
Standard postoperative nutritional management according to institutional clinical pathways, including routine postoperative diet advancement and conventional nutritional support.
Locations (1)
Seoul St. Mary's Hospital
Seoul, Seoul, South Korea