Clinical Research Directory

Inclusion Criteria: * Healthy Chinese subjects aged 18 to 60 years, both male and female. * Wrinkle Severity: Crow's feet graded 2-4; under-eye fine lines graded 2-5; nasolabial folds graded 1-3. * Presence of facial skin laxity and sagging. * Ability to undergo skin examinations and pre-treatment in the designated test areas. * Ability to understand the trial process, participate voluntarily, and sign a written Informed Consent Form (ICF). Exclusion Criteria: * Pregnant or lactating women, or those planning to become pregnant in the near future. * Highly sensitive constitution, history of allergic diseases, or history of allergies to cosmetics. * Presence of skin diseases (e.g., psoriasis, eczema, atopic dermatitis, severe acne) or other chronic systemic diseases. * Skin conditions in the test area such as birthmarks, hyperpigmentation, inflammation, scars, nevi (moles), or hypertrichosis (excessive hair). * Use of anti-inflammatory drugs (e.g., oral or topical corticosteroids) within the past month. * Use of cosmetics or other products with similar efficacy within the past 2 weeks. * Participation in other human clinical trials for cosmetics within the past month. * Any other conditions deemed unsuitable for participation based on clinical assessment.