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Follow-up of a French National Cohort of Patients With Cutaneous Squamous Cell Carcinoma Requiring Systemic Treatment.
Sponsor: University Hospital, Lille
Summary
In the context where advanced cutaneous squamous cell carcinoma (cSCC) is currently a public health issue due to its increasing incidence and where its management is rapidly evolving, it is essential to characterize and monitor changes in therapeutic strategies for patients requiring systemic treatment with adjuvant/neoadjuvant or curative setting. The overall objective of this study is to describe the long-term, real-life management of patients with cSCC requiring systemic therapy, including their clinical characteristics as well as treatment effectiveness and safety. To achieve this aim, the project is based on the establishment of a French national database of patients with cSCC receiving systemic therapy. This is a non-interventional multicenter study involving approximately 30 centers from the French Cutaneous Oncology Group (GCC), including a retrospective phase (from January 2020 for initiation of first-line systemic therapy) followed by a prospective phase. Time perspective is Retrospective and Prospective
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1500
Start Date
2021-07-09
Completion Date
2036-07-15
Last Updated
2026-05-26
Healthy Volunteers
No
Conditions
Interventions
Systemic treatment
Adjuvant Treatment Neoadjuvant Treatment Curative Treatment
Locations (29)
CHU Dijon Bourgogne
Amiens, France
Centre Hospitalier Régional d'Orléans
Annecy, France
CHRU Besançon
Besançon, France
Centre Hospitalier de Blois
Blois, France
Hôpital Avicenne
Bobigny, France
Hôpital Saint André,
Bordeaux, France
Hôpital Ambroise Paré
Boulogne-Billancourt, France
CHU de Caen
Caen, France
CHRU de Tours
Chambray-lès-Tours, France
CHU Estaing
Clermont-Ferrand, France
CHU Henri Mondor
Créteil, France
CHU Dijon Bourgogne
Dijon, France
Centre Hospitalier Le Mans
Le Mans, France
CHU Lille
Lille, France
CHU Dijon Bourgogne
Lyon, France
Hôpital de la Timone
Marseille, France
CHRU Montpellier Hôpital Saint Eloi
Montpellier, France
Hôpital St Eloi
Montpellier, France
CHU Nantes
Nantes, France
CHU de Nice
Nice, France
Centre Hospitalier Régional d'Orléans
Orléans, France
Hôpital Bichat-Claude-Bernard
Paris, France
Hôpital Cochin-Port Royal
Paris, France
Hôpital St Louis
Paris, France
CHU Charles Nicolle
Rouen, France
Institut de Cancérologie de l'Ouest
Saint-Herblain, France
HIA Sainte Anne
Toulon, France
Centre Hospitalier de Valence
Valence, France
CHRU de Nancy
Vandœuvre-lès-Nancy, France