Clinical Research Directory

Inclusion Criteria * Male or female participants diagnosed with RMS and PPMS forms of MS in accordance with the revised McDonald criteria * Evidence of recent disease activity as defined in study protocol * Neurological stability for ≥ 30 days before both screening and first study treatment * Baseline EDSS score between 0 to 6.0 (both inclusive) for RMS patients and between 3.0 and 6.5 (both inclusive) for PPMS patients. Key Exclusion Criteria: * Patient diagnosed with RMS for more than 10 years duration with an EDSS score ≤2.0 at Screening * Patients diagnosed with PPMS \< 10 years with an EDSS at screening ≤ 5.0 or \< 15 years with an EDSS at screening \> 5 * Patient unable to complete or has a contraindication to an MRI * Patient with contraindications and/or severe hypersensitivity to corticosteroids including methylprednisolone or any of the excipients of study drug or interventions defined in the study protocol. * Patient who has currently or history of any of medical conditions described in the study protocol. * Patients who have received or are going to receive any of prohibited medications or treatments defined in the study protocol.