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SII Levels Following PENG Block in Pediatric Hip Surgery
Sponsor: Poznan University of Medical Sciences
Summary
This study is a prospective, randomized, double-blind clinical trial. Its aim is to evaluate whether adding a pericapsular nerve group (PENG) block to spinal anesthesia can reduce the inflammatory response after hip surgery in children. Hip surgery in children can cause a strong stress and inflammatory reaction, which may affect pain after surgery, the need for opioid medications, and recovery. Children aged 3 to 8 years will be randomly assigned to one of two groups: spinal anesthesia alone or spinal anesthesia combined with a PENG block. The main goal is to compare changes in the Systemic Immune-Inflammation Index (SII), a blood-based marker of inflammation, measured before surgery and 24 hours after surgery. Additional outcomes include other inflammatory markers, postoperative pain, opioid use, time to first rescue pain medication, and side effects.
Official title: Pericapsular Nerve Group Block Mitigates Surgical Stress and Enhances Analgesia in Pediatric Hip Surgery: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
3 Years - 8 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2026-06-01
Completion Date
2027-08-31
Last Updated
2026-05-26
Healthy Volunteers
No
Conditions
Interventions
Ropivacaine 0.2% Injectable Solution
Ultrasound-guided regional anesthesia technique targeting the articular branches of the hip joint to provide postoperative analgesia.
0.9%NaCl
Simulated procedure performed to maintain blinding without administration of local anesthetic.
Locations (1)
Poznan University of Medical Sciences
Poznan, Poland