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Multicenter Prospective Study on MRI AI Model for Midline Glioma Subtyping and Prognosis:
Sponsor: Xiangya Hospital of Central South University
Summary
A vision-language model using preoperative MRI and clinical variables has been developed to simultaneously predict three key molecular markers in midline gliomas: H3K27M, IDH, and 1p/19q. This prospective multicenter study will validate the model's accuracy in preoperative molecular subtyping and its value in prognostic assessment and clinical decision-making across multiple neurosurgical centers.
Official title: Application of MRI-Based Artificial Intelligence Models for Preoperative Molecular Subtyping and Prognostic Assessment of Midline Gliomas: A Multicenter Prospective Clinical Study
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2026-05-10
Completion Date
2030-12-31
Last Updated
2026-05-27
Healthy Volunteers
Not specified
Conditions
Locations (1)
Xiangya Hospital of Central South University
Changsha, Hunan, China