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NOT YET RECRUITING
NCT07608445
NA

Physiatry-Led Cancer Prehabilitation During Neoadjuvant Systemic Therapy to Improve Function in Stage III-IVA Gynecologic Cancer Patients

Sponsor: City of Hope Medical Center

View on ClinicalTrials.gov

Summary

This clinical trial studies whether physiatry-led cancer prehabilitation can be used during systemic treatment before surgery (neoadjuvant systemic treatment \[NST\]) to improve function in stage III-IVA gynecologic cancer patients. Treatment of gynecologic cancers presents significant challenges to physical and mental health and patients often experience many challenges following treatment including sleep disturbance, extreme tiredness, sexual dysfunction, and bowel and urinary problems. Patients who have low functioning prior to surgery often have worse outcomes following surgery; however, services to support functional shortages often start after surgery. Physiatry-led cancer prehabilitation is a strategy aimed at reducing post-treatment functional challenges by improving physical and mental function before treatment. It involves physiatry, which is a medical specialty focused on function. Physiatry involvement in prehabilitation allows for the evaluation and management of co-existing conditions, medical supervision, and the coordination of complex plans involving multiple teams. Using physiatry-led cancer prehabilitation during NST may be an effective way to improve function in stage III-IVA gynecologic cancer patients.

Official title: Physiatry-Led Prehabilitation During Neoadjuvant Systemic Treatment Before Surgery for Advanced Gynecological Cancer: A Pilot Feasibility Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

25

Start Date

2026-11-13

Completion Date

2027-11-26

Last Updated

2026-05-27

Healthy Volunteers

Yes

Interventions

OTHER

Educational Intervention

Receive written prehabilitation education materials

OTHER

Goal Setting

Follow and meet prehabilitation goals

OTHER

Interview

Ancillary studies

OTHER

Referral

Receive tailored multidisciplinary referrals

PROCEDURE

Rehabilitation

Attend cancer physiatry consultation

OTHER

Supportive Care

Receive resistance bands, nutritional guidance sources, and tips and resources

OTHER

Survey Administration

Ancillary studies

PROCEDURE

Tailored Intervention

Receive starter prescription

Locations (2)

City of Hope Medical Center

Duarte, California, United States

City of Hope at Irvine Lennar

Irvine, California, United States