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COMPLETED
NCT07610304
PHASE2

Effect of Alpha Tocopherol and Psyllium on Lipid Levels in Dyslipidaemia Patients

Sponsor: NUR International University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to find out whether Vitamin E (Alpha tocopherol), taken alone or together with Psyllium husk (a type of dietary fibre), can improve blood fat levels in adults with dyslipidaemia (abnormal blood levels of two types of fat: cholesterol and triglycerides). The main questions this study aims to answer are: * Does Vitamin E (400 mg/day) alone help lower blood cholesterol and triglyceride levels? * Does combining Vitamin E (400 mg/day) with Psyllium husk (10 g/day) lead to better results compared to participants taking Vitamin E alone? Researchers will compare all three groups i.e. Group A taking Vitamin E alone, Group B taking Vitamin E and Psyllium husk and Group C receiving a placebo (a look alike supplement). The hypothesis of the study is that 'There is a noticeable difference between all the three study groups.' Participants will: * Take their assigned (specific to the concerned group under study) treatment daily for 60 days. * Visit study place every two weeks for follow-up. * Have blood tests done at the beginning and end of the study to check for changes in cholesterol and triglyceride levels.

Official title: Effect Of Alpha Tocopherol Supplementation Alone And In Combination With Psyllium On Serum Lipids In Patients With Dyslipidaemia In Lahore: A Double Blind, Placebo Controlled, Parallel Randomized Control Trial

Key Details

Gender

All

Age Range

40 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2022-06-15

Completion Date

2022-08-20

Last Updated

2026-05-27

Healthy Volunteers

No

Conditions

Interventions

DIETARY_SUPPLEMENT

Alpha tocopherol

400 mg Alpha Tocopherol supplement to be taken daily for a duration of 60 days

COMBINATION_PRODUCT

Combination therapy (Alpha Tocopherol and Psyllium husk)

400 mg Alpha Tocopherol taken along with 10 g psyllium daily for duration of 60 days

OTHER

Placebo Control

A placebo similar to Vitamin E supplement taken daily for 60 days

Locations (1)

Tertiary medical centres: Fatima Memorial Hospital, Services Hospital and National Hospital

Lahore, Pakistan