Clinical Research Directory
Browse clinical research sites, groups, and studies.
guideSEQ: Genomic Understanding, Impact, Decision & Ethics in Prenatal Sequencing
Sponsor: Columbia University
Summary
This study looks at whether genome sequencing should be used more routinely during pregnancy, even when ultrasounds look normal. Genome sequencing can examine nearly all of a baby's genes and may find genetic conditions that standard tests do not detect. Researchers will compare this test with current prenatal testing to see if it provides helpful information for families and doctors. The study will also explore how parents decide what kinds of genetic information they want to receive and how this information affects their experience during pregnancy. The goal is to understand whether genome sequencing can be used in a way that is helpful, responsible, and supportive for families in the future.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1042
Start Date
2026-04-29
Completion Date
2029-07-31
Last Updated
2026-05-29
Healthy Volunteers
Yes
Conditions
Interventions
Genome Sequencing (GS)
Genome sequencing (GS) is a genetic test that involves reading the genome to identify genetic changes (also known as "genetic variants") that can cause differences in human development and disease.
Locations (3)
Boston Childrens Hospital
Boston, Massachusetts, United States
New York Genome Center
New York, New York, United States
Columbia University Irving Medical Center (CUIMC)
New York, New York, United States