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RECRUITING
NCT07610655
NA

Effects of Transcutaneous Vagal Nerve Stimulation on Post-Surgical Return to Consciousness, Delirium, and Depression

Sponsor: Northwestern University

View on ClinicalTrials.gov

Summary

This study will examine whether noninvasive, transcutaneous vagal nerve stimulation (tcVNS) can help restore consciousness in patients in the operating room and the Post Anesthesia Care Unit (PACU). The study will also investigate if tcVNS can expedite discharge from the PACU and examine whether tcVNS administerd in the PACU helps reduce delirium and depression after surgery. The study will also evaluate whether tcVNS speeds cognitive recovery from emergence of anesthesia and surgery.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2026-04-23

Completion Date

2029-05-31

Last Updated

2026-05-28

Healthy Volunteers

No

Interventions

DEVICE

Transcutaneous vagal nerve stimulation

The tcVNS device utilized in this study is not an implanted device, but rather is solely operated outside of the body by affixing it around the patient's ear. The device delivers stimulation of the vagus nerve at designated intensity, interval, and frequency.

DEVICE

Sham (No Treatment)

The stimulator is flipped upside down so that the participant does not receive stimulation of the vagal nerve.

Locations (1)

Northwestern University Feinberg School of Medicine

Chicago, Illinois, United States