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NOT YET RECRUITING
NCT07610759
NA

Inter-Individual Variability in Early Diet-Induced Thermogenesis After a Standardized Meal

Sponsor: Tel Aviv University

View on ClinicalTrials.gov

Summary

This study aims to characterize how individuals differ in their metabolic response to food intake, specifically focusing on early diet-induced thermogenesis (DIT). DIT refers to the increase in energy expenditure that occurs after eating and reflects the body's metabolic response to processing nutrients. Healthy adult participants will complete a single laboratory visit under standardized conditions. Resting metabolic rate will first be measured, followed by consumption of a standardized liquid meal (550 kcal). Energy expenditure will then be continuously monitored for 3 hours using indirect calorimetry. The primary objective is to quantify inter-individual variability in early postprandial thermogenesis. Rather than estimating total daily energy expenditure, this study focuses on the early metabolic response following meal ingestion. Findings will improve understanding of differences in metabolic efficiency between individuals and support future research in metabolism and personalized nutrition.

Official title: Inter-Individual Variability in Early Postprandial Thermogenesis Following a Standardized Liquid Meal

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2026-06

Completion Date

2027-06

Last Updated

2026-05-28

Healthy Volunteers

Yes

Interventions

OTHER

Standardized Liquid Meal

Consumption of a standardized liquid meal (\~550 kcal) under controlled laboratory conditions, followed by continuous measurement of energy expenditure using indirect calorimetry for assessment of postprandial thermogenesis. The procedure is used for measurement purposes only and is not intended as a therapeutic intervention.

Locations (1)

Sylvan Adams Sport Science Institute

Tel Aviv, Israel