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RECRUITING
NCT07611890
PHASE4

Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled Trial

Sponsor: Rawalpindi Institute of Cardiology

View on ClinicalTrials.gov

Summary

After confirming eligibility, written informed consent will be obtained by a trained team member who is not involved in assigning treatment or giving the study medication. Each participant will receive a unique study number to protect privacy. Participants will be randomly assigned to receive one of the study medications using a chance-based method.The study medication will be administered through a vein before placement of the breathing tube. Blood pressure and pulse rate will be measured before the procedure and at several time points after the breathing tube is inserted.

Official title: Comparison of Intravenous Dexmedetomidine and Lignocaine in Reducing Hemodynamic Responses During Laryngoscopy and Endotracheal Intubation In Patients Undergoing Cardiac Surgery at Rawalpindi Institute Of Cardiology- A Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

70

Start Date

2026-05-21

Completion Date

2026-08-21

Last Updated

2026-05-28

Healthy Volunteers

No

Interventions

DRUG

IV dexmedetomidine

0.5 Mcg/kg of Dexmedetomidine will be given 10 minutes before laryngoscopy

DRUG

IV Lignocaine

Patients will be given 1.5 mg/kg of Lignocaine 3 minutes before laryngoscopy

Locations (1)

Rawalpindi Institute of Cardiology

Rawalpindi, Punjab Province, Pakistan