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Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled Trial
Sponsor: Rawalpindi Institute of Cardiology
Summary
After confirming eligibility, written informed consent will be obtained by a trained team member who is not involved in assigning treatment or giving the study medication. Each participant will receive a unique study number to protect privacy. Participants will be randomly assigned to receive one of the study medications using a chance-based method.The study medication will be administered through a vein before placement of the breathing tube. Blood pressure and pulse rate will be measured before the procedure and at several time points after the breathing tube is inserted.
Official title: Comparison of Intravenous Dexmedetomidine and Lignocaine in Reducing Hemodynamic Responses During Laryngoscopy and Endotracheal Intubation In Patients Undergoing Cardiac Surgery at Rawalpindi Institute Of Cardiology- A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2026-05-21
Completion Date
2026-08-21
Last Updated
2026-05-28
Healthy Volunteers
No
Interventions
IV dexmedetomidine
0.5 Mcg/kg of Dexmedetomidine will be given 10 minutes before laryngoscopy
IV Lignocaine
Patients will be given 1.5 mg/kg of Lignocaine 3 minutes before laryngoscopy
Locations (1)
Rawalpindi Institute of Cardiology
Rawalpindi, Punjab Province, Pakistan