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Prediction of Age-Related Hearing Loss Based on Comprehensive Risk Factors
Sponsor: Chinese PLA General Hospital
Summary
This study aims to develop a predictive model for age-related hearing loss (ARHL) based on multi-source risk factors and artificial intelligence techniques. A retrospective analysis will be conducted on 1,000 cases with 15-year longitudinal clinical data, including audiological assessments and noise exposure history. Machine learning algorithms will be employed to construct a predictive model for hearing loss progression. Additionally, a prospective cohort of 100 community-dwelling elderly individuals will be enrolled. Blood samples will be collected for low-abundance targeted proteomics analysis to screen for biomarkers associated with cognitive impairment. This study will establish an early risk identification tool for ARHL and propose strategies for the screening and prevention of dementia in individuals with hearing impairment, thereby providing evidence-based support for early intervention in auditory and cognitive health in the elderly.
Key Details
Gender
All
Age Range
60 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
1000
Start Date
2026-06-01
Completion Date
2027-12-31
Last Updated
2026-05-29
Healthy Volunteers
Yes
Conditions
Interventions
Not applicable- observational study
Not applicable-observational study