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High-Flow Nasal Cannula on Exercise Tolerance in Heart Failure Patients Undergoing Cardiac Rehabilitation.
Sponsor: Universidad de Santiago de Chile
Summary
The goal of this clinical trial is to learn if a high-flow nasal cannula (HFNC) - a device that delivers warm, humidified air through a small tube placed in the nostrils - can improve exercise tolerance in adults with heart failure who are entering a cardiac rehabilitation program. The main questions it aims to answer are: * Can HFNC help people with heart failure exercise for a longer time during a treadmill test? * Does HFNC lower how hard people feel they are working during exercise? Researchers will compare exercise performance with HFNC to exercise performance without HFNC to see if HFNC helps people with heart failure tolerate exercise better. Participants will: * Complete two treadmill exercise tests, one with HFNC and one without, in a randomly assigned order * Wait 48 to 72 hours between the two tests to allow full recovery * Have their heart rate, blood pressure, oxygen level, and breathing rate measured before and after each test
Official title: Effect of High-Flow Nasal Cannula Use on Exercise Tolerance and Physical Performance in Heart Failure Patients Enrolled in a Cardiac Rehabilitation Program: A Randomized Crossover Trial.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
28
Start Date
2026-06-01
Completion Date
2027-03
Last Updated
2026-05-29
Healthy Volunteers
No
Interventions
High-Flow Nasal Cannula (HFNC)
HFNC delivered via AIRVO 2™ (Fisher \& Paykel Healthcare, Auckland, New Zealand) with a nasal cannula at 50-60 L/min, FiO₂ 0.21, temperature 34-37°C. The cannula is removed immediately after the test is completed.
Locations (1)
Complejo Hospitalario San José
Santiago, Santiago Metropolitan, Chile