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Silodosin for Urinary Symptoms in Female Patients With Multiple Sclerosis
Sponsor: Atlantic Health System
Summary
The goal of this clinical trial is to learn if silodosin works to treat lower urinary tract symptoms (LUTS) in female patients with multiple sclerosis (MS). It will also learn about the effect of the drug on voiding parameters. The main questions it aims to answer are: Does silodosin improve lower urinary tract symptoms based on questionnaires? Does silodosin change Uroflowmetry parameters in female patients with MS? Researchers will compare silodosin to a placebo (a look-alike substance that contains no drug) to see if silodosin works to treat LUTS in female patients with MS. Participants will: Take silodosin or a placebo every day for 8 weeks Visit the clinic before initiating the medication and after 8 weeks of taking the medication for questionnaires and tests
Official title: Is Silodosin Effective for Treating Lower Urinary Tract Symptoms in Female Patients With Multiple Sclerosis? A Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-04
Completion Date
2028-04
Last Updated
2026-05-29
Healthy Volunteers
No
Interventions
Silodosin 8 mg
Silodosin 8mg PO qd x8 weeks
Placebo
Identical placebo capsule, 1 capsule PO daily x8 weeks
Locations (1)
Atlantic Health
Morristown, New Jersey, United States