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RECRUITING
NCT07614321
PHASE4

Silodosin for Urinary Symptoms in Female Patients With Multiple Sclerosis

Sponsor: Atlantic Health System

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if silodosin works to treat lower urinary tract symptoms (LUTS) in female patients with multiple sclerosis (MS). It will also learn about the effect of the drug on voiding parameters. The main questions it aims to answer are: Does silodosin improve lower urinary tract symptoms based on questionnaires? Does silodosin change Uroflowmetry parameters in female patients with MS? Researchers will compare silodosin to a placebo (a look-alike substance that contains no drug) to see if silodosin works to treat LUTS in female patients with MS. Participants will: Take silodosin or a placebo every day for 8 weeks Visit the clinic before initiating the medication and after 8 weeks of taking the medication for questionnaires and tests

Official title: Is Silodosin Effective for Treating Lower Urinary Tract Symptoms in Female Patients With Multiple Sclerosis? A Randomized Controlled Trial

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2026-04

Completion Date

2028-04

Last Updated

2026-05-29

Healthy Volunteers

No

Interventions

DRUG

Silodosin 8 mg

Silodosin 8mg PO qd x8 weeks

DRUG

Placebo

Identical placebo capsule, 1 capsule PO daily x8 weeks

Locations (1)

Atlantic Health

Morristown, New Jersey, United States